Bioinformatics Specialization

About Course

Bioinformatics Specialization,When you complete this Specialization, you will learn how to answer many questions in modern biology that have become inseparable from the computational approaches used to solve them. You will also obtain a toolkit of existing software resources built on these computational approaches and that are used by thousands of biologists every day in one of the fastest growing fields in science. Although this Specialization centers on computational topics, you do not need to know how to program in order to complete it. If you are interested in programming, we feature an “Honors Track” (called “hacker track” in previous runs of the course). The Honors Track allows you to implement the bioinformatics algorithms that you will encounter along the way in dozens of automatically graded coding challenges. By completing the Honors Track, you will be a bioinformatics software professional!

Course Content

01. Finding Hidden Messages in DNA (Bioinformatics I)

003 01_check-out-our-wacky-course-intro-video.mp4

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004 02_course-details_instructions.html

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007 01_where-in-the-genome-does-dna-replication-begin-part-1-11-37.mp4

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010 02_where-in-the-genome-does-dna-replication-begin-part-2-06-24.mp4

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011 03_week-1-quiz_exam.html

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012 04_week-1-faqs-optional_instructions.html

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014 05_what-is-pseudocode-optional_instructions.html

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018 01_where-in-the-genome-does-dna-replication-begin-part-3-09-05.mp4

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021 02_where-in-the-genome-does-dna-replication-begin-part-4-04-10.mp4

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022 03_week-2-quiz_exam.html

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023 04_week-2-faqs-optional_instructions.html

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027 01_from-implanted-patterns-to-regulatory-motifs-part-1-10-09.mp4

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030 02_from-implanted-patterns-to-regulatory-motifs-part-2-05-06.mp4

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033 03_from-implanted-patterns-to-regulatory-motifs-part-3-07-22.mp4

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034 04_week-3-quiz_exam.html

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035 05_week-3-faqs-optional_instructions.html

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037 01_week-4-quiz_exam.html

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040 02_how-rolling-dice-helps-us-find-regulatory-motifs-part-1-12-43.mp4

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043 03_how-rolling-dice-helps-us-find-regulatory-motifs-part-2-05-37.mp4

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046 04_how-rolling-dice-helps-us-find-regulatory-motifs-part-3-07-46.mp4

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047 05_week-4-faqs-optional_instructions.html

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049 01_bioinformatics-application-challenge_peer_assignment_instructions.html

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links.txt

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02. Genome Sequencing (Bioinformatics II)

003 01_check-out-our-wacky-course-intro-video.mp4

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004 02_course-details_instructions.html

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007 01_field-trip.mp4

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010 02_what-is-genome-sequencing.mp4

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013 03_exploding-newspapers.mp4

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016 04_the-string-reconstruction-problem.mp4

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019 05_string-reconstruction-as-a-hamiltonian-path-problem.mp4

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022 06_string-reconstruction-as-an-eulerian-path-problem.mp4

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025 07_similar-problems-with-different-fates.mp4

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026 08_week-1-quiz_exam.html

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027 09_week-1-faqs-optional_assembly.html

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031 01_de-bruijn-graphs.mp4

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034 02_eulers-theorem.mp4

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037 03_assembling-read-pairs.mp4

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040 04_de-bruijn-graphs-face-harsh-realities-of-assembly.mp4

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043 05_returning-to-konigsberg.mp4

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044 06_week-2-quiz_exam.html

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045 07_week-2-faqs-optional_assembly.html

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049 01_the-discovery-of-antibiotics.mp4

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052 02_how-do-bacteria-make-antibiotics.mp4

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055 03_sequencing-antibiotics-by-shattering-them-into-pieces.mp4

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058 04_a-brute-force-algorithm-for-cyclopeptide-sequencing.mp4

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061 05_cyclopeptide-sequencing-with-branch-and-bound.mp4

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062 06_week-3-quiz_exam.html

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063 07_week-3-faqs-optional_antibiotics.html

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067 01_adapting-sequencing-for-spectra-with-errors.mp4

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070 02_from-20-to-more-than-100-amino-acids.mp4

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073 03_the-spectral-convolution-saves-the-day.mp4

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076 04_the-truth-about-spectra.mp4

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077 05_week-4-quiz_exam.html

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078 06_week-4-faqs-optional_antibiotics.html

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080 01_bioinformatics-application-challenge_peer_assignment_instructions.html

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links.txt

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03. Comparing Genes, Proteins, and Genomes (Bioinformatics III)

003 01_check-out-our-wacky-course-intro-video.mp4

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004 02_course-details_instructions.html

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007 01_from-sequence-comparison-to-biological-insights.mp4

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010 02_the-alignment-game-and-the-longest-common-subsequence-problem.mp4

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013 03_the-manhattan-tourist-problem.mp4

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016 04_the-change-problem.mp4

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019 05_dynamic-programming-and-backtracking-pointers.mp4

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022 06_from-manhattan-to-the-alignment-graph.mp4

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023 07_week-1-quiz_exam.html

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024 08_week-1-faqs-optional_alignment.html

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028 01_from-global-to-local-alignment.mp4

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029 02_week-2-quiz_exam.html

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030 03_week-2-faqs-optional_alignment.html

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034 01_penalizing-insertions-and-deletions-in-sequence-alignment.mp4

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037 02_space-efficient-sequence-alignment.mp4

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040 03_multiple-sequence-alignment.mp4

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041 04_week-3-quiz_exam.html

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042 05_week-3-faqs-optional_alignment.html

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044 01_week-4-quiz_exam.html

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047 02_transforming-men-into-mice.mp4

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050 03_sorting-by-reversals.mp4

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053 04_breakpoint-theorem.mp4

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056 05_rearrangements-in-tumor-genomes.mp4

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059 06_2-breaks.mp4

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060 07_week-4-faqs-optional_instructions.html

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064 01_breakpoint-graphs.mp4

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067 02_2-break-distance-theorem.mp4

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070 03_rearrangement-hotspots-in-the-human-genome.mp4

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073 04_synteny-block-construction.mp4

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074 05_week-5-quiz_exam.html

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075 06_week-5-faqs-optional_instructions.html

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079 01_bioinformatics-application-challenge_peer_assignment_instructions.html

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links.txt

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04. Molecular Evolution (Bioinformatics IV)

003 01_check-out-our-wacky-course-intro-video.mp4

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004 02_course-details_instructions.html

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007 01_the-fastest-outbreak.mp4

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010 02_transforming-distance-matrices-into-evolutionary-trees.mp4

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013 03_toward-an-algorithm-for-distance-based-phylogeny-construction.mp4

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016 04_additive-phylogeny.mp4

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017 05_week-1-quiz_exam.html

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018 06_week-1-faqs-optional_evolution.html

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022 01_using-least-squares-to-construct-distance-based-phylogenies.mp4

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025 02_ultrametric-trees.mp4

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028 03_the-neighbor-joining-algorithm.mp4

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029 04_week-2-quiz_exam.html

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030 05_week-2-faqs-optional_evolution.html

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034 01_character-based-tree-reconstruction.mp4

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037 02_the-small-parsimony-algorithm.mp4

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040 03_the-large-parsimony-algorithm.mp4

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043 04_evolutionary-tree-reconstruction-in-the-modern-era.mp4

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044 05_week-3-quiz_exam.html

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045 06_week-3-faqs-optional_evolution.html

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049 01_paleontology-meets-computing.mp4

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052 02_decoding-an-ideal-spectrum.mp4

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055 03_from-ideal-to-real-spectra.mp4

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058 04_peptide-sequencing.mp4

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059 05_week-4-quiz_exam.html

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062 01_peptide-identification.mp4

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065 02_spectral-dictionaries.mp4

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068 03_the-ostrich-hemoglobin-riddle.mp4

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071 04_searching-for-post-translational-modifications.mp4

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074 05_spectral-alignment-algorithm.mp4

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075 06_week-5-quiz_exam.html

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077 01_bioinformatics-application-challenge_peer_assignment_instructions.html

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links.txt

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05. Genomic Data Science and Clustering (Bioinformatics V)

003 01_check-out-our-wacky-course-intro-video.mp4

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004 02_course-details_instructions.html

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007 01_which-yeast-genes-are-responsible-for-wine-making.mp4

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010 02_gene-expression-matrices.mp4

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013 03_clustering-as-an-optimization-problem.mp4

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016 04_the-lloyd-algorithm-for-k-means-clustering.mp4

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017 05_week-1-quiz_exam.html

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018 06_week-1-faqs-optional_clustering.html

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022 01_from-hard-to-soft-clustering.mp4

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025 02_from-coin-flipping-to-k-means-clustering.mp4

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028 03_expectation-maximization.mp4

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031 04_soft-k-means-clustering.mp4

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034 05_hierarchical-clustering.mp4

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035 06_week-2-quiz_exam.html

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036 07_week-2-faqs-optional_clustering.html

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038 01_statement-on-this-weeks-material_instructions.html

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040 02_how-have-humans-populated-the-earth_instructions.html

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041 03_week-3-quiz_exam.html

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042 01__resources.html

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links.txt

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06. Finding Mutations in DNA and Proteins (Bioinformatics VI)

003 01_check-out-our-wacky-course-intro-video.mp4

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004 02_course-details_instructions.html

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007 01_why-do-we-map-reads.mp4

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010 02_using-the-trie.mp4

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013 03_from-a-trie-to-a-suffix-tree.mp4

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014 04_how-do-we-find-disease-causing-mutations-week-1_exam.html

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015 05_week-1-faqs-optional_bwt.html

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019 01_string-compression-and-the-burrows-wheeler-transform.mp4

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022 02_inverting-burrows-wheeler.mp4

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025 03_using-burrows-wheeler-for-pattern-matching.mp4

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026 04_week-2-faqs-optional_bwt.html

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030 01_finding-the-matched-patterns.mp4

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033 02_setting-up-checkpoints.mp4

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036 03_inexact-matching.mp4

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039 04_further-applications-of-read-mapping.mp4

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040 05_how-do-we-find-disease-causing-mutations-weeks-2-3_exam.html

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041 06_week-3-faqs-optional_bwt.html

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045 01_classifying-hiv-phenotypes.mp4

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048 02_gambling-with-yakuza.mp4

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051 03_from-a-crooked-casino-to-a-hidden-markov-model.mp4

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054 04_the-decoding-problem.mp4

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057 05_the-viterbi-algorithm.mp4

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060 01_profile-hmms-for-sequence-alignment.mp4

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063 02_classifying-proteins-with-profile-hmms.mp4

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066 03_viterbi-learning.mp4

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069 04_soft-decoding-problem.mp4

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072 05_baum-welch-learning.mp4

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073 06_why-have-biologists-still-not-developed-an-hiv-vaccine-weeks-4-5_exam.html

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074 07_week-5-faqs-optional_hmm.html

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077 01_bioinformatics-application-challenge_peer_assignment_instructions.html

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links.txt

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07. Bioinformatics Capstone Big Data in Biology

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About Course

What Will You Learn?

Course Content

01. Finding Hidden Messages in DNA (Bioinformatics I)

003 01_check-out-our-wacky-course-intro-video.mp4

004 02_course-details_instructions.html

007 01_where-in-the-genome-does-dna-replication-begin-part-1-11-37.mp4

010 02_where-in-the-genome-does-dna-replication-begin-part-2-06-24.mp4

011 03_week-1-quiz_exam.html

012 04_week-1-faqs-optional_instructions.html

014 05_what-is-pseudocode-optional_instructions.html

018 01_where-in-the-genome-does-dna-replication-begin-part-3-09-05.mp4

021 02_where-in-the-genome-does-dna-replication-begin-part-4-04-10.mp4

022 03_week-2-quiz_exam.html

023 04_week-2-faqs-optional_instructions.html

027 01_from-implanted-patterns-to-regulatory-motifs-part-1-10-09.mp4

030 02_from-implanted-patterns-to-regulatory-motifs-part-2-05-06.mp4

033 03_from-implanted-patterns-to-regulatory-motifs-part-3-07-22.mp4

034 04_week-3-quiz_exam.html

035 05_week-3-faqs-optional_instructions.html

037 01_week-4-quiz_exam.html

040 02_how-rolling-dice-helps-us-find-regulatory-motifs-part-1-12-43.mp4

043 03_how-rolling-dice-helps-us-find-regulatory-motifs-part-2-05-37.mp4

046 04_how-rolling-dice-helps-us-find-regulatory-motifs-part-3-07-46.mp4

047 05_week-4-faqs-optional_instructions.html

049 01_bioinformatics-application-challenge_peer_assignment_instructions.html

links.txt

02. Genome Sequencing (Bioinformatics II)

003 01_check-out-our-wacky-course-intro-video.mp4

004 02_course-details_instructions.html

007 01_field-trip.mp4

010 02_what-is-genome-sequencing.mp4

013 03_exploding-newspapers.mp4

016 04_the-string-reconstruction-problem.mp4

019 05_string-reconstruction-as-a-hamiltonian-path-problem.mp4

022 06_string-reconstruction-as-an-eulerian-path-problem.mp4

025 07_similar-problems-with-different-fates.mp4

026 08_week-1-quiz_exam.html

027 09_week-1-faqs-optional_assembly.html

031 01_de-bruijn-graphs.mp4

034 02_eulers-theorem.mp4

037 03_assembling-read-pairs.mp4

040 04_de-bruijn-graphs-face-harsh-realities-of-assembly.mp4

043 05_returning-to-konigsberg.mp4

044 06_week-2-quiz_exam.html

045 07_week-2-faqs-optional_assembly.html

049 01_the-discovery-of-antibiotics.mp4

052 02_how-do-bacteria-make-antibiotics.mp4

055 03_sequencing-antibiotics-by-shattering-them-into-pieces.mp4

058 04_a-brute-force-algorithm-for-cyclopeptide-sequencing.mp4

061 05_cyclopeptide-sequencing-with-branch-and-bound.mp4

062 06_week-3-quiz_exam.html

063 07_week-3-faqs-optional_antibiotics.html

067 01_adapting-sequencing-for-spectra-with-errors.mp4

070 02_from-20-to-more-than-100-amino-acids.mp4

073 03_the-spectral-convolution-saves-the-day.mp4

076 04_the-truth-about-spectra.mp4

077 05_week-4-quiz_exam.html

078 06_week-4-faqs-optional_antibiotics.html

080 01_bioinformatics-application-challenge_peer_assignment_instructions.html

links.txt

03. Comparing Genes, Proteins, and Genomes (Bioinformatics III)

003 01_check-out-our-wacky-course-intro-video.mp4

004 02_course-details_instructions.html

007 01_from-sequence-comparison-to-biological-insights.mp4

010 02_the-alignment-game-and-the-longest-common-subsequence-problem.mp4

013 03_the-manhattan-tourist-problem.mp4

016 04_the-change-problem.mp4

019 05_dynamic-programming-and-backtracking-pointers.mp4

022 06_from-manhattan-to-the-alignment-graph.mp4

023 07_week-1-quiz_exam.html

024 08_week-1-faqs-optional_alignment.html

028 01_from-global-to-local-alignment.mp4

029 02_week-2-quiz_exam.html

030 03_week-2-faqs-optional_alignment.html

034 01_penalizing-insertions-and-deletions-in-sequence-alignment.mp4

037 02_space-efficient-sequence-alignment.mp4

040 03_multiple-sequence-alignment.mp4

041 04_week-3-quiz_exam.html

042 05_week-3-faqs-optional_alignment.html